“The Silver Solution”

Which One?

Crude colloidal silver has been around since the 1900’s, but it contained large silver particles, proteins, silver salts or excessive (even risky) amounts of silver. Until recently, the most powerful silver-based germ killer on the market was silver nitrate.[i] But due to its caustic nature it could only be used in limited ways.

 Colloidal silver formulations fall under four categories: Silver Nucleates, Silver Proteins, Silver halides (i.e., chloride, fluoride, bromide) [ii] and Silver hydrosols.[iii] In every case, the only biologically useful actions of these four categories derives from two attributes only: (a) their total content of “charged” silver ions properly dispersed in a solution and (b) the ion’s “particle size.”[iv] In the case of the first two categories mentioned, the silver compounds are generally inert until they release their silver as an ion, or worse, the carriers inefficiently tie-up the silver ions when speed of delivery is of greatest importance.[v] On top of this handicap, the particle sizes tend to be excessive. In the third category, silver halides cannot attain as great a surface area (exposure) for their silver ions to perform as compared to pure oligodynamic silver particles in just water (i.e., a silver hydrosol, from hydro meaning water, and sol meaning suspension or dispersion).[vi]^, [vii] To their credit, these first three colloidal products are very stable.

 In regards to the last category – silver hydrosols (e.g., silver and water only) – again it is their particle size plus particle charge that creates value and performance to the product. [viii] This suggests that the larger the particle size, the less active sites of silver are available to perform immune related actions.¨[ix]^, [x]^, [xi]^{,[xii], [xiii]} If the particle has lost its charge (i.e., is neutral), it has gone inactive no matter what size it is.[xiv]^{, [xv], [xvi],} [xvii] To their detriment, these products tend to be unstable.[xviii]

 Today we know that the purest, smallest charged silver particles promote powerful immune actions to support health.¨[xix]^, [xx]^, [xxi]^, [xxii]

 State-of-The-Art Silver Nutraceuticals

The best state-of-the-art colloidal silver is Millenia. It is stable with a proven shelf-life, when stored as labeled, of 3 years. It is ultra-pure containing pure silver and water only. Millenia contains no caustic salts and is free of contaminants. It contains NO silver-compounds whatsoever. Why is this important? Because some manufacturers want you to believe that their yellowish or even dark amber, high ppm product is more potent. Discoloration means either (a) larger silver particle sizes, (b) silver-compounds, or (c) oxidized contaminants are present in the formula.

 

When Less Means More

In the authoritative text, CRC Handbook of Chemistry and Physics, it states that even though silver itself is not considered toxic; most of the silver salts are poisonous. Further comments relate how silver-compounds can be absorbed in the circulatory system and that any reduced silver (neutralized silver) can become deposited in the various tissues of the body. This results as a condition known as argyria which is a grayish pigmentation of the skin and mucous membranes. Silver itself promotes effective immunological actions without harm to higher animal tissues.¨[xxiii]

 

Conclusions

The clear choice is Millenia. Our quality precisely determines its safety and effectiveness. All silver works to some extent…though only the best works the best!

 

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[i] Pilcher, JD, Sollmann, T, “Organic, Protein and Colloidal Silver Compounds; Their Antiseptic Efficiency and Silver-Ion Content as a Basis for Their Classification,” The Journal of Laboratory and Clinical Medicine, Sept 29^th, 1922. From the Department of Pharmacology of the Medical School of Western Reserve University, Cleveland, supported by a grant from the Therapeutic Research Committee of the Council on Pharmacy and Chemistry of the American Medical Association.

[ii] Grier, N, “Silver and Its Compounds,” In: Disinfection, Sterilization and Preservation, edited by S. Block, Lea & Febiger, Philadelphia, 1983; p. 375.

[iii] Goetz, A, Tracy, RL, Harris, FS,  “The Oligodynamic Effect of Silver,” In: Silver in Industry, edited by Lawrence Addicks, Reinhold Publishing Corp., NY, 1940; p. 409.

[iv] Goetz, A, “The Oligodynamic Effect of Silver,” In: Silver in Industry, edited by Lawrence Addicks, Reinhold Publishing Corp., NY, 1940p. 405.

[v] Goetz, A, Tracy, RL, Harris, FS,  “The Oligodynamic Effect of Silver,” In: Silver in Industry, edited by Lawrence Addicks, Reinhold Publishing Corp., NY, 1940; p. 401-15.

[vi] Freundlich, H, Colloid & Capillary Chemistry, translated by H. Stafford Hatfield, E.P. Dutton and Co., NY, 1922; p. 394-99.

[vii] Hiemenz, PC, Principles of Colloid and Surface Chemistry, Marcel Dekker, Inc., NY, 1977; p. 210-5.

[viii] Goetz, A, Tracy, RL, Harris, FS,  “The Oligodynamic Effect of Silver,” In: Silver in Industry, edited by Lawrence Addicks, Reinhold Publishing Corp., NY, 1940; p. 401-5.

[ix]  Hiemenz, PC, Principles of Colloid and Surface Chemistry, Marcel Dekker, Inc., NY, 1977; p. 210-5.

[x] Goetz, A, Tracy, RL, Harris, FS,  “The Oligodynamic Effect of Silver,” In: Silver in Industry, edited by Lawrence Addicks, Reinhold Publishing Corp., NY, 1940; p. 412-22.

[xi] Simonetti, N, et al., “Electrochemical Ag+ for Preservative Use,” Applied and Environmental Microbiology, Dec 1992; 58(12):3834.

[xii] Thurman, RB, Gerba, CP, “The Molecular Mechanisms of Copper and Silver Ion Disinfection of Bacteria and Viruses,” CRC Critical Reviews in Environmental Control, 1989; 18(4):295.

[xiii] Zhao, G, Stevens, SE, “Multiple Parameters for the Comprehensive Evaluation of the Susceptibility of Escherichia coli to the Silver Ion,” BioMetals, 1998; 11:28.

[xiv] Pilcher, JD, T Sollmann, “Organic, Protein and Colloidal Silver Compounds; Their Antiseptic Efficiency and Silver-ion Content as a Basis for Their Classification,” The Journal of Laboratory and Clinical Medicine, 1923, p. 301-10.

[xv] Bragg, PD, DJ Rainnie, “The Effect of Silver Ions on the Respiratory Chain of Escherichia coli,” Can J Microbiol, 1974; 20: p. 884.

[xvi] Russel, AD, et al., “Antimicrobial Activity and Action of Silver,” Progress in Medicinal Chemistry, 1994; 31:354.

[xvii] Kim, TN, et al., “Antimicrobial Effects of Metal Ions (Ag⁺, Cu²⁺, Zn²⁺) in Hydroxyapatite,” J Mater Sci Mater Med, 1998; 9:129-34.

[xviii] Bechhold, H, Colloids in Biology and Medicine, D. Van Nostrand Co., 1919; p. 365-8.

[xix] Grier, N, “Silver and Its Compounds,” p. 385; In: Disinfection, Sterilization and Preservation, S. Block, edit., Lea & Febiger, Philadelphia, PA, 1983.

[xx] Feng, QL, et al., “A Mechanistic Study of the Antibacterial effect of Silver Ions on Escherichia coli and Staphylococcus aureus,” J Biomed Mater Res, March 2000; 52:662.

[xxi] Jansson, G, Harms-Ringdahl, M, “Stimulating Effects of Mercuris- and Silver Ions on the Superoxide Anion Production in Human Polymorphonuclear Leukocytes,” Free Radic Res commun, 1993; 18(2):87-98.

[xxii] Berger, TJ, et al., “Electrically Generated Silver Ions: Quantitative Effects on Bacterial and Mammalian Cells,” Anti Microb Agents, 1976; 9(2):357-8.

[xxiii] CRC Handbook of Chemistry and Physics, David R. Lide, Editor-In-chief, 80^th Edition, Boca Raton, FL, 1999-2000; p. 4-27.

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